Ernawati Sinaga, - and Suprihatin, - and Ida Wiryanti, - (2013) ANTICANCER ACTIVITY OF BANGLE HANTU (Zingiber ottensii Val.) RHIZOMES ON BREAST CANCER CELL LINES MCF-7. In: Proceeding Inte rn atio nal The 4th Green Technology Faculty of Science and Technology Islamic of University State Maulana Malik Ibrahim Malang, Malang.
![[img]](http://repository.unas.ac.id/style/images/fileicons/text.png) |
Text
B19-Prosiding-Green Tech Conference.pdf Download (31MB) |
Abstract
Bangle Hanru (Zingiber oltensii Val.) is one of underutilized Zingiberaceae plants which are abundantly grow in Indonesia. It is not commonly used in Indonesian traditional medicine nor as spice in Indonesian culinary system. To increase its utilization, in this study we investigated anticancer activity of the rnethanolic extract of the rhizomes on human breast cancer cell line MCF-7. The antiproliferative effect was measured by comparing the rate of proliferation (doubling time) of cells treated with extract to untreated or control cells using in vitro tetrazolium salt (MIT) assay, and the ability to induce apoptosis was observed using acridine orange-ethidium bromide staining. The results showed that the methanol ic extract significantly inhibit the proliferation of MCF-7, showed by no proliferation occured in cells treated with 20 µg/mL extract (the lowest concentration used in the experiment) while only 25% cells left alive after 24 hours incubation with 80 µg/mL extract (the highest concentation used in the experiment). The extract also showed
| Item Type: | Conference or Workshop Item (Paper) |
|---|---|
| Subjects: | Q Science > QL Zoology Q Science > QR Microbiology |
| Depositing User: | BPSI Unas |
| Date Deposited: | 30 Aug 2018 09:44 |
| Last Modified: | 11 Sep 2020 00:27 |
| URI: | http://repository.unas.ac.id/id/eprint/251 |
Actions (login required)
 |
View Item |
